The European collaborative project PreDicta was launched in October 2010 in Athens (Greece). The €7,8 million initiative funded in large part by the European Commission  will endeavour to answer a simple but unanswered question: Why do asthma symptoms persist?

Based on the observation that childhood asthma usually occurs after a viral respiratory tract infection, the central hypothesis of the project is that repeated, acute infection-mediated events may reprogram the immune system to predispose towards a chronic inflammation pattern.

The PreDicta consortium integrated 14 partners from 9 European countries that worked together during five years under the coordination of Prof Nikos Papadopoulos from the National and Kapodistrian University of Athens. Leading core units of the consortium substantially contributed to our current understanding of the role of respiratory infections in asthma, the immuno-inflammatory processes involved and the development of diagnostic and therapeutic approaches for this disease. This academic effort employed the latest technologies of molecular biology, virology and cytology and was complemented by the participation of BIOMAY, an Austrian company fully dedicated to the development of novel diagnostic and immunotherapeutic approaches for allergic diseases and asthma.

The final objective of PreDicta was, by the end of the programme, to be able to predict more accurately the predisposing risk factors for the development of respiratory allergies and to interfere more effectively with the disease process by targeting causative agents rather than symptoms.

GA²LEN supported PreDicta with networking and dissemination.

Predicta FP7 contract no: 260895

Predicta’s presentation video:

http://www.youtube.com/watch?v=4ZosDQnwKMw

Participant’s organization name Principal Investigator Country
NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS Nikolaos Papadopoulos Greece
IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE Sebastian L Johnston UK
MEDIZINISCHE UNIVERSITAET WIEN Rudolf Valenta Austria
SCHWEIZERISCHES FORSCHUNGSINSTITUT FUER HOCHGEBIRGSKLIMA UND MEDIZIN IN DAVOS Mubeccel Akdis Switzerland
BIOMEDICAL RESEARCH FOUNDATION, ACADEMY OF ATHENS Vangelis Andreakos Greece
UNIVERSYTET MEDYCZNY W LODZI Marek L. Kowalski Poland
UNIVERSITEIT GENT Claus Bachert Belgium
PHILIPPS UNIVERSITAET MARBURG Harald Renz Germany
TURUN YLIOPISTO Tytti Vuorinen Finland
UNIVERSITAETSKLINIKUM ERLANGEN Susetta Finotto Germany
BIOMAY AG Angela Neubauer Austria
INSERM – TRANSFERT Dahlia Fasquel France
VARSINAIS-SUOMEN SAIRAANHOITOPIIRIN KUNTAYHTYMA Tuomas Jartti Finland

Learn about other projects